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1

Emotion Detection in Suicide Notes using Maximum Entropy Classification

Wicentowski, Richard, Sydes, Matthew R.

Journal:

Biomedical Informatics Insights

Year:

2012

Language:

english

File:

PDF, 560 KB

english, 2012

2

Repurposing Metformin as Therapy for Prostate Cancer within the STAMPEDE Trial Platform

Gillessen, Silke, Gilson, Clare, James, Nick, Adler, Amanda, Sydes, Matthew R., Clarke, Noel

Journal:

European Urology

Year:

2016

Language:

english

File:

PDF, 511 KB

english, 2016

3

Adaptive designs in clinical trials: why use them, and how to run and report them

Pallmann, Philip, Bedding, Alun W., Choodari-Oskooei, Babak, Dimairo, Munyaradzi, Flight, Laura, Hampson, Lisa V., Holmes, Jane, Mander, Adrian P., Odondi, Lang’o, Sydes, Matthew R., Villar, Sofía S.,

Journal:

Year:

2018

Language:

english

File:

PDF, 887 KB

english, 2018

4

Practical methods for incorporating summary time-to-event data into meta-analysis

Jayne F Tierney, Lesley A Stewart, Davina Ghersi, Sarah Burdett, Matthew R Sydes

Journal:

Year:

2007

Language:

english

File:

PDF, 869 KB

english, 2007

5

A Thorn in the Flesch: Observations on the Unreliability of Computer-Based Readability Formulae

Matthew Sydes, James Hartley

Journal:

British Journal of Educational Technology

Year:

1997

Language:

english

File:

PDF, 149 KB

english, 1997

6

Are Structured Abstracts Easier to Read Than Traditional Ones?

James Hartley, Matthew Sydes

Journal:

Journal of Research in Reading

Year:

1997

Language:

english

File:

PDF, 315 KB

english, 1997

7

Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise

Sarah L. Gulliford, Mike Partridge, Matthew R. Sydes, Steve Webb, Philip M. Evans, David P. Dearnaley

Journal:

Radiotherapy and Oncology

Year:

2012

Language:

english

File:

PDF, 249 KB

english, 2012

8

More multiarm randomised trials of superiority are needed

Parmar, Mahesh K B, Carpenter, James, Sydes, Matthew R

Journal:

Year:

2014

Language:

english

File:

PDF, 199 KB

english, 2014

9

Outcomes and endpoints in cancer trials: bridging the divide

Wilson, Michelle K, Collyar, Deborah, Chingos, Diana T, Friedlander, Michael, Ho, Tony W, Karakasis, Katherine, Kaye, Stan, Parmar, Mahesh K B, Sydes, Matthew R, Tannock, Ian F, Oza, Amit M

Journal:

The Lancet Oncology

Year:

2015

Language:

english

File:

PDF, 609 KB

english, 2015

10

Comments on ‘A modest proposal for dropping poor arms in clinical trials’ by Proschan and Dodd

Bratton, Daniel J., Choodari-Oskooei, Babak, Phillips, Patrick P. J., Sydes, Matthew R., Parmar, Mahesh K. B.

Journal:

Statistics in Medicine

Year:

2015

Language:

english

File:

PDF, 48 KB

english, 2015

11

Adding abiraterone or docetaxel to long-term hormone therapy for prostate cancer: directly randomised data from the STAMPEDE multi-arm, multi-stage platform protocol

Sydes, Matthew R, Spears, Melissa R, Mason, Malcolm D, Clarke, Noel W, Dearnaley, David P, de Bono, Johann S, Attard, Gert, Chowdhury, Simon, Cross, Bill, Gillessen, Silke, Malik, Zaf, Jones, Rob, Par

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 933 KB

english, 2018

12

Triggered or routine site monitoring visits for randomised controlled trials: results of TEMPER, a prospective, matched-pair study

Stenning, Sally P, Cragg, William J, Joffe, Nicola, Diaz-Montana, Carlos, Choudhury, Rahela, Sydes, Matthew R, Meredith, Sarah

Journal:

Clinical Trials

Year:

2018

Language:

english

File:

PDF, 391 KB

english, 2018

13

BA08: An open-label, single-arm, non-randomised, phase 2 trial of cisplatin, methotrexate and vinblastine (CMV) for pure squamous cell cancer of the urinary tract

Griffiths, Gareth O., Cowan, Richard A., Grigor, Kenneth M., Uscinska, Barbara M., Sydes, Matthew, Russell, Martin, Gupta, Sudeep

Journal:

Year:

2019

Language:

english

File:

PDF, 608 KB

english, 2019

14

Adjuvant or early salvage radiotherapy for the treatment of localised and locally advanced prostate cancer: a prospectively planned systematic review and meta-analysis of aggregate data

Vale, Claire L, Fisher, David, Kneebone, Andrew, Parker, Christopher, Pearse, Maria, Richaud, Pierre, Sargos, Paul, Sydes, Matthew R, Brawley, Christopher, Brihoum, Meryem, Brown, Chris, Chabaud, Sylv

Journal:

Lancet (London, England)

Year:

2020

File:

PDF, 680 KB

2020

15

Late Gastrointestinal Toxicity After Dose-Escalated Conformal Radiotherapy for Early Prostate Cancer: Results From the UK Medical Research Council RT01 Trial (ISRCTN47772397)

Isabel Syndikus, Rachel C. Morgan, Matthew R. Sydes, John D. Graham, David P. Dearnaley

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2010

Language:

english

File:

PDF, 389 KB

english, 2010

16

Expression of Bcl-2, p53, and MDM2 in Localized Prostate Cancer With Respect to the Outcome of Radical Radiotherapy Dose Escalation

Roy Vergis, Catherine M. Corbishley, Karen Thomas, Alan Horwich, Robert Huddart, Vincent Khoo, Ros Eeles, Matthew R. Sydes, Colin S. Cooper, David Dearnaley, Chris Parker

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2010

Language:

english

File:

PDF, 175 KB

english, 2010

17

Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial

Matthew R Sydes, Mahesh KB Parmar, Nicholas D James, Noel W Clarke, David P Dearnaley, Malcolm D Mason, Rachel C Morgan, Karen Sanders, Patrick Royston

Journal:

Year:

2009

Language:

english

File:

PDF, 631 KB

english, 2009

18

Flexible trial design in practice – dropping and adding arms in STAMPEDE: a multi-arm multi-stage randomised controlled trial

Matthew R Sydes, Nicholas D James, Malcolm D Mason, Noel W Clarke, Claire Amos, John Anderson, Johann de Bono, David P Dearnaley, John Dwyer, Gordana Jovic, Alastair Ritchie, Martin Russell, Karen San

Journal:

Year:

2011

Language:

english

File:

PDF, 130 KB

english, 2011

19

Reflections on attempted Anglo–Japanese collaboration on STAMPEDE: A randomized controlled trial for men with prostate cancer

Matthew R Sydes, Shin Egawa, Karen Sanders, Claire Amos, Noel Clarke, Takahiro Kimura, Nicholas D James

Journal:

International Journal of Urology

Year:

2011

Language:

english

File:

PDF, 75 KB

english, 2011

20

The quality of life of men with locally advanced prostate cancer during neoadjuvant hormone therapy: data from the Medical Research Council RT01 trial (ISRCTN 47772397)

Richard J. Stephens, David P. Dearnaley, Richard Cowan, Matthew Sydes, Sharon Naylor, Lesley Fallowfield, on behalf of all the RT01 collaborators

Journal:

BJU International

Year:

2007

Language:

english

File:

PDF, 167 KB

english, 2007

21

Radiotherapy and androgen deprivation in combination after local surgery (RADICALS): A new Medical Research Council/National Cancer Institute of Canada phase III trial of adjuvant treatment after radical prostatectomy

Chris Parker, Matthew R. Sydes, Charles Catton, Howard Kynaston, John Logue, Claire Murphy, Rachel C. Morgan, Kilian Mellon, Chris Morash, Wendy Parulekar, Mahesh K.B. Parmar, Heather Payne, Colleen S

Journal:

BJU International

Year:

2007

Language:

english

File:

PDF, 125 KB

english, 2007

22

Systemic therapy for advancing or metastatic prostate cancer (STAMPEDE): a multi-arm, multistage randomized controlled trial

Nicholas D. James, Matthew R. Sydes, Noel W. Clarke, Malcolm D. Mason, David P. Dearnaley, John Anderson, Richard J. Popert, Karen Sanders, Rachel C. Morgan, Jim Stansfeld, John Dwyer, John Masters, M

Journal:

BJU International

Year:

2009

Language:

english

File:

PDF, 181 KB

english, 2009

23

Re: Ute Ganswindt, Arnulf Stenzl, Michael Bamberg and Claus Belka. Adjuvant Radiotherapy for Patients with Locally Advanced Prostate Cancer—A New Standard? Eur Urol 2008;54:528–42

Chris Parker, Matthew R. Sydes

Journal:

European Urology

Year:

2009

Language:

english

File:

PDF, 64 KB

english, 2009

24

Re: Ofer Yossepowitch, Anders Bjartell, James A. Eastham, et al. Positive Surgical Margins in Radical Prostatectomy: Outlining the Problem and Its Long-Term Consequences. Eur Urol 2009;55:87–99

Howard Kynaston, Christopher C. Parker, Matthew R. Sydes

Journal:

European Urology

Year:

2009

Language:

english

File:

PDF, 53 KB

english, 2009

25

Survival after recurrent osteosarcoma: Data from 3 European Osteosarcoma Intergroup (EOI) randomized controlled trials

Hans Gelderblom, Rachel C. Jinks, Matthew Sydes, Vivien H.C. Bramwell, Martine van Glabbeke, Robert J. Grimer, Pancras C.W. Hogendoorn, Anne McTiernan, Ian J. Lewis, Marianne A. Nooij, Antonie H.M. Ta

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 286 KB

english, 2011

26

Interim monitoring of efficacy data is important and appropriate

Matthew R. Sydes, Mahesh K.B. Parmar

Journal:

Journal of Clinical Epidemiology

Year:

2008

Language:

english

File:

PDF, 65 KB

english, 2008

27

The dose–response of the anal sphincter region – An analysis of data from the MRC RT01 trial

Florian Buettner, Sarah L. Gulliford, Steve Webb, Matthew R. Sydes, David P. Dearnaley, Mike Partridge

Journal:

Radiotherapy and Oncology

Year:

2012

Language:

english

File:

PDF, 547 KB

english, 2012

28

Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: first results from the MRC RT01 randomised controlled trial

David P Dearnaley, Matthew R Sydes, John D Graham, Edwin G Aird, David Bottomley, Richard A Cowan, Robert A Huddart, Chakiath C Jose, John HL Matthews, Jeremy Millar, A Rollo Moore, Rachel C Morgan, J

Journal:

The Lancet Oncology

Year:

2007

Language:

english

File:

PDF, 420 KB

english, 2007

29

Intrinsic markers of tumour hypoxia and angiogenesis in localised prostate cancer and outcome of radical treatment: a retrospective analysis of two randomised radiotherapy trials and one surgical cohort study

Roy Vergis, Catherine M Corbishley, Andrew R Norman, Jaclyn Bartlett, Sameer Jhavar, Michael Borre, Sara Heeboll, Alan Horwich, Robert Huddart, Vincent Khoo, Ros Eeles, Colin Cooper, Matthew Sydes, Da

Journal:

The Lancet Oncology

Year:

2008

Language:

english

File:

PDF, 335 KB

english, 2008

30

Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled trials

David P Dearnaley, Malcolm D Mason, Mahesh KB Parmar, Karen Sanders, Matthew R Sydes

Journal:

The Lancet Oncology

Year:

2009

Language:

english

File:

PDF, 192 KB

english, 2009

31

Potential pitfalls in the design and reporting of clinical trials

Matthew R Sydes, Ruth E Langley

Journal:

The Lancet Oncology

Year:

2010

Language:

english

File:

PDF, 179 KB

english, 2010

32

Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial

Nicholas D James, Matthew R Sydes, Malcolm D Mason, Noel W Clarke, John Anderson, David P Dearnaley, John Dwyer, Gordana Jovic, Alastair WS Ritchie, J Martin Russell, Karen Sanders, George N Thalmann,

Journal:

The Lancet Oncology

Year:

2012

Language:

english

File:

PDF, 244 KB

english, 2012

33

Re: Andrew J. Stephenson, Michel Bolla, Alberto Briganti, et al. Postoperative Radiation Therapy for Pathologically Advanced Prostate Cancer After Radical Prostatectomy. Eur Urol 2012;61:443–51

Matthew R. Sydes, Claire Vale, Andrew Kneebone, Maria Pearse, Pierre Richaud, Jayne F. Tierney, Christopher C. Parker

Journal:

European Urology

Year:

2012

Language:

english

File:

PDF, 69 KB

english, 2012

34

Adjuvant Radiotherapy After Prostatectomy: Does Waiting for a Detectable Prostate-Specific Antigen Level Make Sense?: In Regard to King CR (Int J Radiat Oncol Biol Phys 2011;80:1–3)

Charles N. Catton, Christopher C. Parker, Matthew R. Sydes

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2011

Language:

english

File:

PDF, 42 KB

english, 2011

35

Evaluating the relationship between erectile dysfunction and dose received by the penile bulb: Using data from a randomised controlled trial of conformal radiotherapy in prostate cancer (MRC RT01, ISRCTN47772397)

Stephen A. Mangar, Matthew R. Sydes, Helen L. Tucker, Jerome Coffey, Syed A. Sohaib, Stefano Gianolini, Steve Webb, Vincent S. Khoo, David P. Dearnaley

Journal:

Radiotherapy and Oncology

Year:

2006

Language:

english

File:

PDF, 199 KB

english, 2006

36

The early toxicity of escalated versus standard dose conformal radiotherapy with neo-adjuvant androgen suppression for patients with localised prostate cancer: Results from the MRC RT01 trial (ISRCTN47772397)

David P. Dearnaley, Matthew R. Sydes, Ruth E. Langley, John D. Graham, Robert A. Huddart, Isabel Syndikus, John H.L. Matthews, Christopher D. Scrase, Chakiath C. Jose, John Logue, Richard J. Stephens

Journal:

Radiotherapy and Oncology

Year:

2007

Language:

english

File:

PDF, 536 KB

english, 2007

37

A comparison of dose–volume constraints derived using peak and longitudinal definitions of late rectal toxicity

Sarah L. Gulliford, Mike Partridge, Matthew R. Sydes, Jervoise Andreyev, David P. Dearnaley

Journal:

Radiotherapy and Oncology

Year:

2010

Language:

english

File:

PDF, 353 KB

english, 2010

38

Using Implicit Information to Identify Smoking Status in Smoke-blind Medical Discharge Summaries

Richard Wicentowski, Matthew R. Sydes

Journal:

Journal of the American Medical Informatics Association

Year:

2008

Language:

english

File:

PDF, 64 KB

english, 2008

39

Prostate cancer staging tables—A predictive model for the UK

Simon R.J. Bott, Mark Emberton, Matthew R. Sydes

Journal:

British Journal of Medical and Surgical Urology

Year:

2008

Language:

english

File:

PDF, 131 KB

english, 2008

40

When should radiotherapy be used after radical prostatectomy? The RADICALS-RT Trial

Christopher C. Parker, Noel W. Clarke, Howard Kynaston, Matthew R. Sydes

Journal:

British Journal of Medical and Surgical Urology

Year:

2010

Language:

english

File:

PDF, 96 KB

english, 2010

41

Presence of chemotherapy-induced toxicity predicts improved survival in patients with localised extremity osteosarcoma treated with doxorubicin and cisplatin: A report from the European Osteosarcoma Intergroup

Anne McTiernan, Rachel C. Jinks, Matthew R. Sydes, Barbara Uscinska, Jane M. Hook, Martine van Glabbeke, Vivien Bramwell, Ian J. Lewis, Antonie H.M. Taminiau, Marianne A. Nooij, Pancras C.W. Hogendoor

Journal:

European Journal of Cancer

Year:

2012

Language:

english

File:

PDF, 461 KB

english, 2012

42

Flexible trial design in practice - stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial

Matthew R Sydes, Mahesh KB Parmar, Malcolm D Mason, Noel W Clarke, Claire Amos, John Anderson, Johann de Bono, David P Dearnaley, John Dwyer, Charlene Green, Gordana Jovic, Alastair WS Ritchie, J Mart

Journal:

Year:

2012

Language:

english

File:

PDF, 323 KB

english, 2012

43

Postoperative Radiotherapy After Radical Prostatectomy: Let's Work Together to Tackle the Known Unknowns

Parker, Christopher C., Sydes, Matthew R.

Journal:

European Urology

Year:

2014

Language:

english

File:

PDF, 112 KB

english, 2014

44

MP53-20 THE PREDICTIVE VALUE OF 2-YEAR POST-TREATMENT BIOPSY AFTER PROSTATE CANCER CONFORMAL RADIOTHERAPY FOR FUTURE OVERALL SURVIVAL AND BIOCHEMICAL FAILURE. THE RESULTS OF THE UK MRC RT01 TRIAL.

Kass-iliyya, Antoine, Jovic, Gordana, Sydes, Matthew, Fisher, Cyril, Murphy, Claire, Nicol, David, Dearnaley, David

Journal:

The Journal of Urology

Year:

2014

Language:

english

File:

PDF, 328 KB

english, 2014

45

Re: Sanoj Punnen, Matthew R. Cooperberg, Anthony V. D’Amico, et al. Management of Biochemical Recurrence After Primary Treatment of Prostate Cancer: A Systematic Review of the Literature. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2013.05.025

Parker, Chris, Sydes, Matthew R., Kynaston, Howard

Journal:

European Urology

Year:

2013

Language:

english

File:

PDF, 151 KB

english, 2013

46

The need for a cultural shift from two-arm to multi-arm RCTS

Matthew R Sydes,Mahesh KB Parmar

Journal:

Year:

2013

Language:

english

File:

PDF, 120 KB

english, 2013

47

Can we deliver randomized trials of focal therapy in prostate cancer?

Ahmed, Hashim U., Berge, Viktor, Bottomley, David, Cross, William, Heer, Rakesh, Kaplan, Richard, Leslie, Tom, Parker, Chris, Relton, Clare, Stephens, Richard, Sydes, Matthew R., Turnbull, Lindsay, va

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2014

Language:

english

File:

PDF, 785 KB

english, 2014

48

Clinical trial designs for rare diseases: Studies developed and discussed by the International Rare Cancers Initiative

Bogaerts, Jan, Sydes, Matthew R., Keat, Nicola, McConnell, Andrea, Benson, Al, Ho, Alan, Roth, Arnaud, Fortpied, Catherine, Eng, Cathy, Peckitt, Clare, Coens, Corneel, Pettaway, Curtis, Arnold, Dirk,

Journal:

European Journal of Cancer

Year:

2015

Language:

english

File:

PDF, 425 KB

english, 2015

49

Sharing data from clinical trials: the rationale for a controlled access approach

Sydes, Matthew R, Johnson, Anthony L, Meredith, Sarah K, Rauchenberger, Mary, South, Annabelle, Parmar, Mahesh

Journal:

Year:

2015

Language:

english

File:

PDF, 411 KB

english, 2015

50

Reported use of data monitoring committees in the main published reports of randomized controlled trials: a cross-sectional study

Sydes, Matthew R, Altman, Douglas G, Babiker, Abdel B, Parmar, Mahesh K B, Spiegelhalter, David J

Journal:

Clinical Trials

Year:

2004

Language:

english

File:

PDF, 302 KB

english, 2004